Ph.D., Laboratory for Inherited Metabolic Disorders, Medical Hospital Olomouc, Czech Republic

 

 Main areas of research

  1. Separation techniques: liquid chromatography, capillary electrophoresis,

 

  1. Mass spectrometry: QqQ, Orbitrap, ESI, high-throughput flow injection analysis, MS2/MS3 HR/AM fragmentation

 

  1. Inherited Metabolic Disorders: Nucleotide metabolism, expanded newborn screening, LC/MS for IMD

 

  1. Therapeutic drug monitoring: tyrosine kinase inhibitors, immunosuppressants, antihypertensives, methotrexate

 

  1. Metabolomics: targeted/untargeted approach - LC/MS, FIA/MS, Quadrupole analyzers, Orbitrap, data processing, interpretation, analysis of bodyfluids, cells, tissues – clinical applications

 

  1. Drug metabolisation: detail analysis of metabolites in bodyfluids, identification and confirmation of metabolites

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